PIK3CA-Related Overgrowth Spectrum (PROS)

Patient Support Programs for PIK3CA Related Overgrowth Spectrum (PROS) - ASP Health

PIK3CA-Related Overgrowth Spectrum (PROS)

In the PIK3CA-related overgrowth spectrum (PROS), several body parts grow beyond their normal size due to mutations in the PIK3CA gene. Proteins produced by this gene are involved in regulating cell growth, division, and survival. When a baby is born, these symptoms are usually visible, so doctors can diagnose a PROS condition at birth. In some cases, it occurs later in childhood.


Signs and Symptoms

In PROS, there are numerous subtypes, including CLAPO syndrome, CLOVES syndrome, DCMO, DMEG, FAH/FAO/HHML, FAVA, FIL, HMEG, KTS, LON, macrodactyly, MCAP, and muscular hemihyperplasia (HH). There are a wide range of symptoms depending on which part of the body overgrows, including intellectual disability, seizures, and autism when the brain is involved, as well as blood clots when blood vessels are affected.


There is a somatic mutation in the PIK3CA gene that causes PROS. There are many activated mutations in the PI3KCA gene that are linked to different syndromes with some genetic overlap between the different syndromes.

Affected Populations

There are several different PROS syndromes, so it is impossible to determine the exact incidence and prevalence rates. These conditions are typically diagnosed at birth or in early childhood.


ASP Health Patient Assistance Program

The cost of healthcare is rising every day. It becomes impossible to adjust to the present scenario. Patient Assistance Programs or Prescription Assistance Programs are managed by pharmaceutical companies, healthcare providers, and foundations. Prescription assistance is a service that helps patients find the right medication for them.

The non-profit organization ASP Health is dedicated to assisting people in obtaining the necessary medical care.

What does ASP Health do for patients?

There are many ways ASP Health assists. The ASP Health program offers prescription drugs to people without insurance or with limited insurance coverage. As part of its mission to provide patients with medication, ASP Health collaborates with pharmaceutical companies and organizations.

ASP Health offers a variety of healthcare services and products at affordable rates. You can enroll free of cost in any program if you are eligible.

You can request assistance or simply dial 405-283-3244, we will take care of you and your health.

From completing documents to obtaining the proper prescriptions, ASP Health will assist you in every way.