Adult-Onset Leukoencephalopathy with Axonal Spheroids and Pigmented Glia (ALSP)

Patient Support Programs for Adult-Onset Leukoencephalopathy with Axonal Spheroids and Pigmented Glia (ALSP)

Adult-Onset Leukoencephalopathy with Axonal Spheroids and Pigmented Glia (ALSP)


Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) is a rare, progressive neurological disease, which causes white matter in the brain to waste away (leukodystrophy), resulting in lesions in certain brain areas due to variants in the CSF1R gene (colony-stimulating factor-1 receptor). According to some studies, ALSP accounts for 10 to 25% of adult-onset leukodystrophies. Eventually, people with this disorder develop dementia and later decline into a vegetative state due to lesions in this white matter, which disrupt personality, thinking, and muscle functions.

ASP Health provides prescription drugs and/or medical equipment that is funded by pharmaceutical companies or government programs to patients who need them.

adult-onset-leukoencephalopathy

Signs and Symptoms


There are mild psychological or cognitive symptoms associated with ALSP, but motor function disturbances, such as walking difficulties, falling, and slow movement are rare. Psychological, cognitive, and motor symptoms occur together as damage to the brain becomes more extensive.

Causes


A gene variant for CSF1R causes ALSP, which affects the protein colony-stimulating factor-1 receptor, which is found on cell membranes throughout the central nervous system (the brain and spinal cord). In the body, this receptor facilitates cell growth and specialization, so that cells are able to take on specific functions.


Affected Populations


ALSP is estimated to affect 10,000 people in the United States, with similar estimates in Europe and Japan. After the onset of symptoms, the life expectancy ranges from 2 to 30 years, with an average life expectancy of 8 years.


adult-onset-leukoencephalopathy
adult-onset-leukoencephalopathy

What ASP Health Assist?


Nowadays, everyone worries about how to purchase out-of-pocket medications as their costs are increasing day by day. Drug manufacturers and healthcare organizations come up with a solution. They offer several programs to deal with healthcare costs, from which you can select whatever suits you. Every program has its own requirements.

ASP Health assists with patient assistance. Patient assistance programs provide medications at an affordable cost or no cost. As ASP Health facilitates prior authorization, we ensure that the patient receives the most appropriate medication while reducing drug costs.

ASP Health can provide critical information on programs that aid with the cost of their prescription medications. ASP Health's non-profit foundation is committed to helping people get the health care they need.

If you need help, filling out the application form or have any doubts, we are available at every step whenever you face an issue. You can apply through our online portal or give us a call at Call us today at 702-551-5212